p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but does not impact on body weight or glucose homeostasis in diet-induced obesity.

BCL-2 proteins have been implicated in the control of glucose homeostasis and metabolism in different cell types. Thus, the aim of this study was to determine the role of the pro-apoptotic BH3-only protein, p53-upregulated-modulator-of-apoptosis (PUMA), in metabolic changes mediated by diet-induced...

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Detalles Bibliográficos
Autores principales: Litwak, Sara A., Loh, Kim, Stanley, William J., Pappas, Evan G., Wali, Jibran A., Selck, Claudia, Strasser, Andreas, Thomas, Helen E., Gurzov, Esteban N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817123/
https://www.ncbi.nlm.nih.gov/pubmed/27033313
http://dx.doi.org/10.1038/srep23802

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