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Angiopoietin-like Protein 2 Is a Multistep Regulator of Inflammatory Neovascularization in a Murine Model of Age-related Macular Degeneration

Choroidal neovascularization (CNV) is a pathogenic process of age-related macular degeneration, a vision-threatening disease. The retinal pigment epithelium and macrophages both influence CNV development. However, the underlying mechanisms remain obscure. Here, we focus on Angptl2 (angiopoietin-like...

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Detalles Bibliográficos
Autores principales:	Hirasawa, Manabu, Takubo, Keiyo, Osada, Hideto, Miyake, Seiji, Toda, Eriko, Endo, Motoyoshi, Umezawa, Kazuo, Tsubota, Kazuo, Oike, Yuichi, Ozawa, Yoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Molecular Bases of Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817169/ https://www.ncbi.nlm.nih.gov/pubmed/26839315 http://dx.doi.org/10.1074/jbc.M115.710186

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