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First reported cases: renal denervation with secondgeneration multi-electrode catheter via brachial and radial access

Renal denervation is a minimally invasive procedure that aims to reduce brain–kidney sympathetic cross-talk. Despite the negative results of the recent SYMPLICITY HTN-3 trial, the procedure is considered safe and has been associated with many beneficial effects, including the reversal of hypertensiv...

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Detalles Bibliográficos
Autores principales: Heradien, MJ, Brink, PA, Augustyn, J, Saaiman, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Clinics Cardive Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817202/
https://www.ncbi.nlm.nih.gov/pubmed/26956499
http://dx.doi.org/10.5830/CVJA-2015-089
Descripción
Sumario:Renal denervation is a minimally invasive procedure that aims to reduce brain–kidney sympathetic cross-talk. Despite the negative results of the recent SYMPLICITY HTN-3 trial, the procedure is considered safe and has been associated with many beneficial effects, including the reversal of hypertensive heart disease substrate and the prevention of cardiac arrhythmia. The first-generation radiofrequency catheter system featured a monopolar catheter that required sequential singlepoint energy application, followed by rotation, partial withdrawal of the catheter and re-application of energy. The latest generation device features four electrodes configured in a helical arrangement that can simultaneously ablate in four quadrants of the vessel circumference. Renal denervation via brachial or radial arterial access with the second-generation system has not been described before.