Deacetylation of Fungal Exopolysaccharide Mediates Adhesion and Biofilm Formation

The mold Aspergillus fumigatus causes invasive infection in immunocompromised patients. Recently, galactosaminogalactan (GAG), an exopolysaccharide composed of galactose and N-acetylgalactosamine (GalNAc), was identified as a virulence factor required for biofilm formation. The molecular mechanisms...

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Detalles Bibliográficos
Autores principales: Lee, Mark J., Geller, Alexander M., Bamford, Natalie C., Liu, Hong, Gravelat, Fabrice N., Snarr, Brendan D., Le Mauff, François, Chabot, Joseé, Ralph, Benjamin, Ostapska, Hanna, Lehoux, Mélanie, Cerone, Robert P., Baptista, Stephanie D., Vinogradov, Evgeny, Stajich, Jason E., Filler, Scott G., Howell, P. Lynne, Sheppard, Donald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817252/
https://www.ncbi.nlm.nih.gov/pubmed/27048799
http://dx.doi.org/10.1128/mBio.00252-16

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