Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis

Aspergillus fumigatus, an opportunistic fungal pathogen, spreads in the environment by releasing numerous conidia that are capable of reaching the small alveolar airways of mammalian hosts. In otherwise healthy individuals, macrophages are responsible for rapidly phagocytosing and eliminating these...

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Detalles Bibliográficos
Autores principales: Schlam, Daniel, Canton, Johnathan, Carreño, Marvin, Kopinski, Hannah, Freeman, Spencer A., Grinstein, Sergio, Fairn, Gregory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817266/
https://www.ncbi.nlm.nih.gov/pubmed/27048806
http://dx.doi.org/10.1128/mBio.02242-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817266/
https://www.ncbi.nlm.nih.gov/pubmed/27048806
http://dx.doi.org/10.1128/mBio.02242-15

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