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Sialic Acid Is Required for Neuronal Inhibition by Soluble MAG but not for Membrane Bound MAG
Myelin-Associated Glycoprotein (MAG), a major inhibitor of axonal growth, is a member of the immunoglobulin (Ig) super-family. Importantly, MAG (also known as Siglec-4) is a member of the Siglec family of proteins (sialic acid-binding, immunoglobulin-like lectins), MAG binds to complex gangliosides,...
Autores principales: | Al-Bashir, Najat, Mellado, Wilfredo, Filbin, Marie T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817280/ https://www.ncbi.nlm.nih.gov/pubmed/27065798 http://dx.doi.org/10.3389/fnmol.2016.00021 |
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