The challenge to improve the response of biomaterials to the physiological environment

New applications of biomaterials often require advanced structures containing synthetic and natural components that are tuned to provide properties unique to a specific application. We discuss how structural characteristics of biomaterials, especially hydrophilic ones, can be used in conjunction wit...

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Detalles Bibliográficos
Autores principales: Peppas, Nicholas A., Clegg, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817319/
https://www.ncbi.nlm.nih.gov/pubmed/27047671
http://dx.doi.org/10.1093/rb/rbw012
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author Peppas, Nicholas A.
Clegg, John R.
author_facet Peppas, Nicholas A.
Clegg, John R.
author_sort Peppas, Nicholas A.
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description New applications of biomaterials often require advanced structures containing synthetic and natural components that are tuned to provide properties unique to a specific application. We discuss how structural characteristics of biomaterials, especially hydrophilic ones, can be used in conjunction with non-ideal thermodynamics to develop advanced medical systems. We show a number of examples of biocompatible, intelligent biomaterials that can be used for organ replacement, biosensors, precise drug delivery over days or weeks, and regenerative medicine.
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spelling pubmed-48173192016-04-04 The challenge to improve the response of biomaterials to the physiological environment Peppas, Nicholas A. Clegg, John R. Regen Biomater Reviews New applications of biomaterials often require advanced structures containing synthetic and natural components that are tuned to provide properties unique to a specific application. We discuss how structural characteristics of biomaterials, especially hydrophilic ones, can be used in conjunction with non-ideal thermodynamics to develop advanced medical systems. We show a number of examples of biocompatible, intelligent biomaterials that can be used for organ replacement, biosensors, precise drug delivery over days or weeks, and regenerative medicine. Oxford University Press 2016-06 2016-03-10 /pmc/articles/PMC4817319/ /pubmed/27047671 http://dx.doi.org/10.1093/rb/rbw012 Text en © The Author(s) 2016. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Peppas, Nicholas A.
Clegg, John R.
The challenge to improve the response of biomaterials to the physiological environment
title The challenge to improve the response of biomaterials to the physiological environment
title_full The challenge to improve the response of biomaterials to the physiological environment
title_fullStr The challenge to improve the response of biomaterials to the physiological environment
title_full_unstemmed The challenge to improve the response of biomaterials to the physiological environment
title_short The challenge to improve the response of biomaterials to the physiological environment
title_sort challenge to improve the response of biomaterials to the physiological environment
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817319/
https://www.ncbi.nlm.nih.gov/pubmed/27047671
http://dx.doi.org/10.1093/rb/rbw012
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