A time- and cost-effective strategy to sequence mammalian Y Chromosomes: an application to the de novo assembly of gorilla Y

The mammalian Y Chromosome sequence, critical for studying male fertility and dispersal, is enriched in repeats and palindromes, and thus, is the most difficult component of the genome to assemble. Previously, expensive and labor-intensive BAC-based techniques were used to sequence the Y for a handf...

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Detalles Bibliográficos
Autores principales: Tomaszkiewicz, Marta, Rangavittal, Samarth, Cechova, Monika, Sanchez, Rebeca Campos, Fescemyer, Howard W., Harris, Robert, Ye, Danling, O'Brien, Patricia C.M., Chikhi, Rayan, Ryder, Oliver A., Ferguson-Smith, Malcolm A., Medvedev, Paul, Makova, Kateryna D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817776/
https://www.ncbi.nlm.nih.gov/pubmed/26934921
http://dx.doi.org/10.1101/gr.199448.115

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