Degradation dynamics of microRNAs revealed by a novel pulse-chase approach

The regulation of miRNAs is critical to the definition of cell identity and behavior in normal physiology and disease. To date, the dynamics of miRNA degradation and the mechanisms involved in remain largely obscure, in particular, in higher organisms. Here, we developed a pulse-chase approach based...

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Detalles Bibliográficos
Autores principales: Marzi, Matteo J., Ghini, Francesco, Cerruti, Benedetta, de Pretis, Stefano, Bonetti, Paola, Giacomelli, Chiara, Gorski, Marcin M., Kress, Theresia, Pelizzola, Mattia, Muller, Heiko, Amati, Bruno, Nicassio, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817778/
https://www.ncbi.nlm.nih.gov/pubmed/26821571
http://dx.doi.org/10.1101/gr.198788.115

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