Overlap between Parkinson disease and Alzheimer disease in ABCA7 functional variants

OBJECTIVE: Given their reported function in phagocytosis and clearance of protein aggregates in Alzheimer disease (AD), we hypothesized that variants in ATP-binding cassette transporter A7 (ABCA7) might be involved in Parkinson disease (PD). METHODS: ABCA7 variants were identified using whole-exome...

Descripción completa

Detalles Bibliográficos
Autores principales: Nuytemans, Karen, Maldonado, Lizmarie, Ali, Aleena, John-Williams, Krista, Beecham, Gary W., Martin, Eden, Scott, William K., Vance, Jeffery M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817903/
https://www.ncbi.nlm.nih.gov/pubmed/27066581
http://dx.doi.org/10.1212/NXG.0000000000000044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817903/
https://www.ncbi.nlm.nih.gov/pubmed/27066581
http://dx.doi.org/10.1212/NXG.0000000000000044

Ejemplares similares