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Overlap between Parkinson disease and Alzheimer disease in ABCA7 functional variants

OBJECTIVE: Given their reported function in phagocytosis and clearance of protein aggregates in Alzheimer disease (AD), we hypothesized that variants in ATP-binding cassette transporter A7 (ABCA7) might be involved in Parkinson disease (PD). METHODS: ABCA7 variants were identified using whole-exome...

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Detalles Bibliográficos
Autores principales:	Nuytemans, Karen, Maldonado, Lizmarie, Ali, Aleena, John-Williams, Krista, Beecham, Gary W., Martin, Eden, Scott, William K., Vance, Jeffery M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817903/ https://www.ncbi.nlm.nih.gov/pubmed/27066581 http://dx.doi.org/10.1212/NXG.0000000000000044

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