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In silico prioritization based on coexpression can aid epileptic encephalopathy gene discovery

OBJECTIVE: To evaluate the performance of an in silico prioritization approach that was applied to 179 epileptic encephalopathy candidate genes in 2013 and to expand the application of this approach to the whole genome based on expression data from the Allen Human Brain Atlas. METHODS: PubMed search...

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Detalles Bibliográficos
Autores principales: Oliver, Karen L., Lukic, Vesna, Freytag, Saskia, Scheffer, Ingrid E., Berkovic, Samuel F., Bahlo, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817907/
https://www.ncbi.nlm.nih.gov/pubmed/27066588
http://dx.doi.org/10.1212/NXG.0000000000000051