U1 Adaptor Oligonucleotides Targeting BCL2 and GRM1 Suppress Growth of Human Melanoma Xenografts In Vivo

U1 Adaptor is a recently discovered oligonucleotide-based gene-silencing technology with a unique mechanism of action that targets nuclear pre-mRNA processing. U1 Adaptors have two distinct functional domains, both of which must be present on the same oligonucleotide to exert their gene-silencing fu...

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Detalles Bibliográficos
Autores principales: Goraczniak, Rafal, Wall, Brian A, Behlke, Mark A, Lennox, Kim A, Ho, Eric S, Zaphiros, Nikolas H, Jakubowski, Christopher, Patel, Neil R, Zhao, Steven, Magaway, Carlo, Subbie, Stacey A, Jenny Yu, Lumeng, LaCava, Stephanie, Reuhl, Kenneth R, Chen, Suzie, Gunderson, Samuel I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817935/
https://www.ncbi.nlm.nih.gov/pubmed/23673539
http://dx.doi.org/10.1038/mtna.2013.24

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