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Functional Stability of the Human Kappa Opioid Receptor Reconstituted in Nanodiscs Revealed by a Time-Resolved Scintillation Proximity Assay
Long-term functional stability of isolated membrane proteins is crucial for many in vitro applications used to elucidate molecular mechanisms, and used for drug screening platforms in modern pharmaceutical industry. Compared to soluble proteins, the understanding at the molecular level of membrane p...
Autores principales: | Hansen, Randi Westh, Wang, Xiaole, Golab, Agnieszka, Bornert, Olivier, Oswald, Christine, Wagner, Renaud, Martinez, Karen Laurence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817975/ https://www.ncbi.nlm.nih.gov/pubmed/27035823 http://dx.doi.org/10.1371/journal.pone.0150658 |
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