The qEEG Signature of Selective NMDA NR2B Negative Allosteric Modulators; A Potential Translational Biomarker for Drug Development

The antidepressant activity of the N-methyl-D-aspartate (NMDA) receptor channel blocker, ketamine, has led to the investigation of negative allosteric modulators (NAMs) selective for the NR2B receptor subtype. The clinical development of NR2B NAMs would benefit from a translational pharmacodynamic b...

Descripción completa

Detalles Bibliográficos
Autores principales: Keavy, Deborah, Bristow, Linda J., Sivarao, Digavalli V., Batchelder, Margaret, King, Dalton, Thangathirupathy, Srinivasan, Macor, John E., Weed, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817977/
https://www.ncbi.nlm.nih.gov/pubmed/27035340
http://dx.doi.org/10.1371/journal.pone.0152729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817977/
https://www.ncbi.nlm.nih.gov/pubmed/27035340
http://dx.doi.org/10.1371/journal.pone.0152729

Ejemplares similares