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Cognitive impairment and stroke in elderly patients
We reviewed current knowledge about the interaction between stroke and vascular risk factors and the development of cognitive impairment and dementia. Stroke is increasingly recognized as an important cause of cognitive problems and has been implicated in the development of both Alzheimer’s disease...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818041/ https://www.ncbi.nlm.nih.gov/pubmed/27069366 http://dx.doi.org/10.2147/VHRM.S75306 |
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author | Lo Coco, Daniele Lopez, Gianluca Corrao, Salvatore |
author_facet | Lo Coco, Daniele Lopez, Gianluca Corrao, Salvatore |
author_sort | Lo Coco, Daniele |
collection | PubMed |
description | We reviewed current knowledge about the interaction between stroke and vascular risk factors and the development of cognitive impairment and dementia. Stroke is increasingly recognized as an important cause of cognitive problems and has been implicated in the development of both Alzheimer’s disease and vascular dementia. The prevalence of cognitive impairment after stroke is high, and their combined effects significantly increase the cost of care and health resource utilization, with reflections on hospital readmissions and increased mortality rates. There is also substantial evidence that vascular risk factors (such as hypertension, diabetes, obesity, dyslipidemia, and tobacco smoking) are independently associated with an increased risk of cognitive decline and dementia. Thus, a successful management of these factors, as well as optimal acute stroke management, might have a great impact on the development of cognitive impairment. Notwithstanding, the pathological link between cognitive impairment, stroke, and vascular risk factors is complex and still partially unclear so that further studies are needed to better elucidate the boundaries of this relationship. Many specific pharmacological treatments, including anticholinergic drugs and antihypertensive medications, and nonpharmacological approaches, such as diet, cognitive rehabilitation, and physical activity, have been studied for patients with vascular cognitive impairment, but the optimal care is still far away. Meanwhile, according to the most recent knowledge, optimal stroke care should also include cognitive assessment in the short and long term, and great efforts should be oriented toward a multidisciplinary approach, including quality-of-life assessment and support of caregivers. |
format | Online Article Text |
id | pubmed-4818041 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-48180412016-04-11 Cognitive impairment and stroke in elderly patients Lo Coco, Daniele Lopez, Gianluca Corrao, Salvatore Vasc Health Risk Manag Review We reviewed current knowledge about the interaction between stroke and vascular risk factors and the development of cognitive impairment and dementia. Stroke is increasingly recognized as an important cause of cognitive problems and has been implicated in the development of both Alzheimer’s disease and vascular dementia. The prevalence of cognitive impairment after stroke is high, and their combined effects significantly increase the cost of care and health resource utilization, with reflections on hospital readmissions and increased mortality rates. There is also substantial evidence that vascular risk factors (such as hypertension, diabetes, obesity, dyslipidemia, and tobacco smoking) are independently associated with an increased risk of cognitive decline and dementia. Thus, a successful management of these factors, as well as optimal acute stroke management, might have a great impact on the development of cognitive impairment. Notwithstanding, the pathological link between cognitive impairment, stroke, and vascular risk factors is complex and still partially unclear so that further studies are needed to better elucidate the boundaries of this relationship. Many specific pharmacological treatments, including anticholinergic drugs and antihypertensive medications, and nonpharmacological approaches, such as diet, cognitive rehabilitation, and physical activity, have been studied for patients with vascular cognitive impairment, but the optimal care is still far away. Meanwhile, according to the most recent knowledge, optimal stroke care should also include cognitive assessment in the short and long term, and great efforts should be oriented toward a multidisciplinary approach, including quality-of-life assessment and support of caregivers. Dove Medical Press 2016-03-24 /pmc/articles/PMC4818041/ /pubmed/27069366 http://dx.doi.org/10.2147/VHRM.S75306 Text en © 2016 Lo Coco et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Review Lo Coco, Daniele Lopez, Gianluca Corrao, Salvatore Cognitive impairment and stroke in elderly patients |
title | Cognitive impairment and stroke in elderly patients |
title_full | Cognitive impairment and stroke in elderly patients |
title_fullStr | Cognitive impairment and stroke in elderly patients |
title_full_unstemmed | Cognitive impairment and stroke in elderly patients |
title_short | Cognitive impairment and stroke in elderly patients |
title_sort | cognitive impairment and stroke in elderly patients |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818041/ https://www.ncbi.nlm.nih.gov/pubmed/27069366 http://dx.doi.org/10.2147/VHRM.S75306 |
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