Cargando…

Development of a Bifunctional Andrographolide-Based Chemical Probe for Pharmacological Study

Andrographolide (ANDRO) is a lactone diterpenoid compound present in the medicinal plant Andrographis paniculata which is clinically applied for multiple human diseases in Asia and Europe. The pharmacological activities of andrographolide have been widely demonstrated, including anti-inflammation, a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hsu, Ya-Hsin, Hsu, Yu-Ling, Liu, Sheng-Hung, Liao, Hsin-Chia, Lee, Po-Xuan, Lin, Chao-Hsiung, Lo, Lee-Chiang, Fu, Shu-Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818061/ https://www.ncbi.nlm.nih.gov/pubmed/27035713 http://dx.doi.org/10.1371/journal.pone.0152770

Ejemplares similares

Andrographolide and its fluorescent derivative inhibit the main proteases of 2019-nCoV and SARS-CoV through covalent linkage
por: Shi, Tzu-Hau, et al.
Publicado: (2020)

Andrographolide impedes cancer stemness and enhances radio-sensitivity in oral carcinomas via miR-218 activation
por: Yang, Po-Yu, et al.
Publicado: (2016)

Andrographolide in atherosclerosis: integrating network pharmacology and in vitro pharmacological evaluation
por: Shi, Shuai, et al.
Publicado: (2022)

Andrographolide relieved pathological pain generated by spared nerve injury model in mice
por: Wang, Huang-Chi, et al.
Publicado: (2018)

Andrographolide Relieves Post-Operative Wound Pain but Affects Local Angiogenesis
por: Lin, Yi-Lo, et al.
Publicado: (2022)

Experimental and Clinical Pharmacology of Andrographis paniculata and Its Major Bioactive Phytoconstituent Andrographolide
por: Jayakumar, Thanasekaran, et al.
Publicado: (2013)

Investigating pharmacological mechanisms of andrographolide on non-alcoholic steatohepatitis (NASH): A bioinformatics approach of network pharmacology
por: Li, Lei, et al.
Publicado: (2021)

Andrographolide
por: Yan, Yu, et al.
Publicado: (2018)

Therapeutic Potential of Andrographolide Isolated from the Leaves of Andrographis paniculata Nees for Treating Lung Adenocarcinomas
por: Tung, Yu-Tang, et al.
Publicado: (2013)

Development of chimeric and bifunctional antagonists for CLR/RAMP receptors
por: Chang, Chia Lin, et al.
Publicado: (2019)

Andrographolide enhances the anti-metastatic effect of radiation in Ras-transformed cells via suppression of ERK–mediated MMP-2 activity
por: Yu, Chih-Chia, et al.
Publicado: (2018)

Deduction of Novel Genes Potentially Involved in Osteoblasts of Rheumatoid Arthritis Using Next-Generation Sequencing and Bioinformatic Approaches
por: Chen, Yi-Jen, et al.
Publicado: (2017)

Galectin-7 regulates keratinocyte proliferation and differentiation through JNK-miR-203-p63 signaling
por: Chen, Hung-Lin, et al.
Publicado: (2016)

Systematic Analysis of Differential Expression Profile in Rheumatoid Arthritis Chondrocytes Using Next-Generation Sequencing and Bioinformatics Approaches
por: Chen, Yi-Jen, et al.
Publicado: (2018)

Systematic Analysis of Transcriptomic Profile of Chondrocytes in Osteoarthritic Knee Using Next-Generation Sequencing and Bioinformatics
por: Chen, Yi-Jen, et al.
Publicado: (2018)

Waist Circumference Is More Closely Associated with Hypogonadism than Is Hyperglycemia, Independent of BMI in Middle-Aged Men
por: Hsu, Po-Sheng, et al.
Publicado: (2021)

U-Shaped Optical Fiber Probes Coated with Electrically Doped GQDs for Humidity Measurements
por: Wen, Hsin-Yi, et al.
Publicado: (2021)

Correlation between Visual Acuity and Optical Coherence Tomography Angiography Parameters in Unilateral Idiopathic Epiretinal Membrane
por: Fang, I-Mo, et al.
Publicado: (2020)

Real-Time Monitoring the Cytotoxic Effect of Andrographolide on Human Oral Epidermoid Carcinoma Cells
por: Liao, Heng-Yi, et al.
Publicado: (2022)

Exploring the mechanism of andrographolide in the treatment of gastric cancer through network pharmacology and molecular docking
por: Yadav, Ravi Prakash, et al.
Publicado: (2022)

Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species
por: Needham, Lisa-Maria, et al.
Publicado: (2018)

Discrimination of Methicillin-resistant Staphylococcus aureus by MALDI-TOF Mass Spectrometry with Machine Learning Techniques in Patients with Staphylococcus aureus Bacteremia
por: Kong, Po-Hsin, et al.
Publicado: (2022)

Andrographolide Against Lung Cancer-New Pharmacological Insights Based on High-Throughput Metabolomics Analysis Combined with Network Pharmacology
por: Luo, Wen, et al.
Publicado: (2021)

Pharmacological Activation Of Aldehyde Dehydrogenase 2 Protects Against Heatstroke-Induced Acute Lung Injury by Modulating Oxidative Stress and Endothelial Dysfunction
por: Tsai, Hsiao-Ya, et al.
Publicado: (2021)

Study on the Antitumor Effect and Glycolysis of Andrographolide in Anaplastic Thyroid Carcinoma
por: Yang, Ke, et al.
Publicado: (2021)

Multi-Targeting Andrographolide, a Novel NF-κB Inhibitor, as a Potential Therapeutic Agent for Stroke
por: Yang, Chih-Hao, et al.
Publicado: (2017)

Oral Bioavailability Enhancement and Anti-Fatigue Assessment of the Andrographolide Loaded Solid Dispersion
por: Yen, Ching-Chi, et al.
Publicado: (2020)

Study on the mechanism of andrographolide activation
por: Cai, Qihan, et al.
Publicado: (2022)

Erlotinib-Conjugated Iron Oxide Nanoparticles as a Smart Cancer-Targeted Theranostic Probe for MRI
por: Ali, Ahmed Atef Ahmed, et al.
Publicado: (2016)

Characteristics of Gut Microbiota in Small for Gestational Age Infants with Very Low Birth Weight
por: Chang, Hung-Yang, et al.
Publicado: (2022)

Correction to ‘Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species’
por: Needham, Lisa-Maria, et al.
Publicado: (2018)

Environmental DNA (eDNA) Metabarcoding in the Fish Market and Nearby Seafood Restaurants in Taiwan Reveals the Underestimation of Fish Species Diversity in Seafood
por: Lee, Hung-Tai, et al.
Publicado: (2021)

Combination of system biology to probe the anti-viral activity of andrographolide and its derivative against COVID-19
por: Khanal, Pukar, et al.
Publicado: (2021)

Spatial Analysis of Ambient PM(2.5) Exposure and Bladder Cancer Mortality in Taiwan
por: Yeh, Hsin-Ling, et al.
Publicado: (2017)

Activity of andrographolide against chikungunya virus infection
por: Wintachai, Phitchayapak, et al.
Publicado: (2015)

Protective effects of andrographolide against cerebral ischemia-reperfusion injury in mice
por: Li, Yan, et al.
Publicado: (2021)

Bacterial community analysis identifies Klebsiella pneumoniae as a native symbiotic bacterium in the newborn Protobothrops mucrosquamatus
por: Su, Hung-Yuan, et al.
Publicado: (2023)

A network-based pharmacological investigation to identify the mechanistic regulatory pathway of andrographolide against colorectal cancer
por: Janani, Balakarthikeyan, et al.
Publicado: (2022)

Sulforaphane-Induced Cell Mitotic Delay and Inhibited Cell Proliferation via Regulating CDK5R1 Upregulation in Breast Cancer Cell Lines
por: Hung, Chao-Ming, et al.
Publicado: (2023)

Bifunctional non-noble metal oxide nanoparticle electrocatalysts through lithium-induced conversion for overall water splitting
por: Wang, Haotian, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_niiu2pthmd2pjiu0dpse2298c4