Naringenin prevents TGF-β1 secretion from breast cancer and suppresses pulmonary metastasis by inhibiting PKC activation

BACKGROUND: Targeting the TGF-β1 pathway for breast cancer metastasis therapy has become an attractive strategy. We have previously demonstrated that naringenin significantly reduced TGF-β1 levels in bleomycin-induced lung fibrosis and effectively prevented pulmonary metastases of tumors. This raise...

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Detalles Bibliográficos
Autores principales: Zhang, Fayun, Dong, Wenjuan, Zeng, Wenfeng, Zhang, Lei, Zhang, Chao, Qiu, Yuqi, Wang, Luoyang, Yin, Xiaozhe, Zhang, Chunling, Liang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818388/
https://www.ncbi.nlm.nih.gov/pubmed/27036297
http://dx.doi.org/10.1186/s13058-016-0698-0

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