Molecular alterations in the TCR signaling pathway in patients with aplastic anemia

BACKGROUND: A previous study has demonstrated a significantly increased CD3ζ gene expression level in aplastic anemia (AA). However, the mechanism underlying the upregulated CD3ζ mRNA expression level and that of T cell activation signaling molecules in AA patients remains unclear. Thus, we investig...

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Detalles Bibliográficos
Autores principales: Li, Bo, Guo, Lixing, Zhang, Yuping, Xiao, Yankai, Wu, Mingjuan, Zhou, Lingling, Chen, Shaohua, Yang, Lijian, Lu, Xiang, Li, Yangqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818392/
https://www.ncbi.nlm.nih.gov/pubmed/27036622
http://dx.doi.org/10.1186/s13045-016-0261-6

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