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Long-term outcomes and healthcare utilization following critical illness – a population-based study

BACKGROUND: The purpose of this study was to examine hospital mortality, long-term mortality, and health service utilization among critically ill patients. We also determined whether these outcomes differed according to demographic and clinical characteristics. METHODS: We conducted a retrospective...

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Autores principales: Hill, A. D., Fowler, R. A., Pinto, R., Herridge, M. S., Cuthbertson, B. H., Scales, D. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818427/
https://www.ncbi.nlm.nih.gov/pubmed/27037030
http://dx.doi.org/10.1186/s13054-016-1248-y
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author Hill, A. D.
Fowler, R. A.
Pinto, R.
Herridge, M. S.
Cuthbertson, B. H.
Scales, D. C.
author_facet Hill, A. D.
Fowler, R. A.
Pinto, R.
Herridge, M. S.
Cuthbertson, B. H.
Scales, D. C.
author_sort Hill, A. D.
collection PubMed
description BACKGROUND: The purpose of this study was to examine hospital mortality, long-term mortality, and health service utilization among critically ill patients. We also determined whether these outcomes differed according to demographic and clinical characteristics. METHODS: We conducted a retrospective cohort study of adults (age ≥18 years) who survived admission to an intensive care unit (ICU) in Ontario, Canada, between 1 April 2002 and 31 March 2012, excluding isolated admissions to step-down or intermediate ICUs, coronary care ICUs, or cardiac surgery ICUs. Adults (age ≥18 years) who survived an acute hospitalization that did not include an ICU stay formed the comparator group. The primary outcome was mortality following hospital discharge. Secondary outcomes were healthcare utilization, including emergency room admissions and hospital readmissions during follow-up. RESULTS: Over the study interval, 500,124 patients were admitted to ICUs and 420,187 (84 %) survived to hospital discharge. Median follow-up for survivors was 5.3 (interquartile range 2.5, 8.2) years. Patients admitted to an ICU were more likely to subsequently visit the emergency department, be readmitted to the hospital and ICU, receive home care support, require rehabilitation, and be admitted for long-term care. Those requiring more resources within the ICU required more resources after discharge. One-third of patients admitted to the ICU died during long-term follow-up, with overall probabilities of death of 11 % and 29 % at 1 year and 5 years, respectively. In the adjusted analysis, there was an increasing hazard of death with increasing age, reaching a hazard ratio of 18.08 (95 % confidence interval 16.60–19.68) for those ≥85 years of age compared with those aged 18–24 years. CONCLUSIONS: Healthcare utilization after hospital discharge was higher among ICU patients, and also among those requiring more healthcare resources during their ICU admission, than among all hospitalized patients as a group. One-third of ICU patients died within the 5 years following discharge, and age was the most influential determinant of outcome. These findings should help target post–ICU discharge services for high-risk groups and better inform goals-of-care discussions for elderly critically ill patients. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13054-016-1248-y) contains supplementary material, which is available to authorized users.
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spelling pubmed-48184272016-04-03 Long-term outcomes and healthcare utilization following critical illness – a population-based study Hill, A. D. Fowler, R. A. Pinto, R. Herridge, M. S. Cuthbertson, B. H. Scales, D. C. Crit Care Research BACKGROUND: The purpose of this study was to examine hospital mortality, long-term mortality, and health service utilization among critically ill patients. We also determined whether these outcomes differed according to demographic and clinical characteristics. METHODS: We conducted a retrospective cohort study of adults (age ≥18 years) who survived admission to an intensive care unit (ICU) in Ontario, Canada, between 1 April 2002 and 31 March 2012, excluding isolated admissions to step-down or intermediate ICUs, coronary care ICUs, or cardiac surgery ICUs. Adults (age ≥18 years) who survived an acute hospitalization that did not include an ICU stay formed the comparator group. The primary outcome was mortality following hospital discharge. Secondary outcomes were healthcare utilization, including emergency room admissions and hospital readmissions during follow-up. RESULTS: Over the study interval, 500,124 patients were admitted to ICUs and 420,187 (84 %) survived to hospital discharge. Median follow-up for survivors was 5.3 (interquartile range 2.5, 8.2) years. Patients admitted to an ICU were more likely to subsequently visit the emergency department, be readmitted to the hospital and ICU, receive home care support, require rehabilitation, and be admitted for long-term care. Those requiring more resources within the ICU required more resources after discharge. One-third of patients admitted to the ICU died during long-term follow-up, with overall probabilities of death of 11 % and 29 % at 1 year and 5 years, respectively. In the adjusted analysis, there was an increasing hazard of death with increasing age, reaching a hazard ratio of 18.08 (95 % confidence interval 16.60–19.68) for those ≥85 years of age compared with those aged 18–24 years. CONCLUSIONS: Healthcare utilization after hospital discharge was higher among ICU patients, and also among those requiring more healthcare resources during their ICU admission, than among all hospitalized patients as a group. One-third of ICU patients died within the 5 years following discharge, and age was the most influential determinant of outcome. These findings should help target post–ICU discharge services for high-risk groups and better inform goals-of-care discussions for elderly critically ill patients. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13054-016-1248-y) contains supplementary material, which is available to authorized users. BioMed Central 2016-03-31 2016 /pmc/articles/PMC4818427/ /pubmed/27037030 http://dx.doi.org/10.1186/s13054-016-1248-y Text en © Hill et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Hill, A. D.
Fowler, R. A.
Pinto, R.
Herridge, M. S.
Cuthbertson, B. H.
Scales, D. C.
Long-term outcomes and healthcare utilization following critical illness – a population-based study
title Long-term outcomes and healthcare utilization following critical illness – a population-based study
title_full Long-term outcomes and healthcare utilization following critical illness – a population-based study
title_fullStr Long-term outcomes and healthcare utilization following critical illness – a population-based study
title_full_unstemmed Long-term outcomes and healthcare utilization following critical illness – a population-based study
title_short Long-term outcomes and healthcare utilization following critical illness – a population-based study
title_sort long-term outcomes and healthcare utilization following critical illness – a population-based study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818427/
https://www.ncbi.nlm.nih.gov/pubmed/27037030
http://dx.doi.org/10.1186/s13054-016-1248-y
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