Hydrogen sulfide modulates chromatin remodeling and inflammatory mediator production in response to endotoxin, but does not play a role in the development of endotoxin tolerance

BACKGROUND: Pretreatment with low doses of LPS (lipopolysaccharide, bacterial endotoxin) reduces the pro-inflammatory response to a subsequent higher LPS dose, a phenomenon known as endotoxin tolerance. Moreover, hydrogen sulfide (H(2)S), an endogenous gaseous mediator (gasotransmitter) can exert an...

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Detalles Bibliográficos
Autores principales: Rios, Ester C. S., Soriano, Francisco G., Olah, Gabor, Gerö, Domokos, Szczesny, Bartosz, Szabo, Csaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818437/
https://www.ncbi.nlm.nih.gov/pubmed/27042162
http://dx.doi.org/10.1186/s12950-016-0119-2

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