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Differential effects of hyaluronan synthase 3 deficiency after acute vs chronic liver injury in mice

BACKGROUND: Hyaluronan (HA) is a ubiquitous extracellular matrix (ECM) glycosaminoglycan synthesized by three different enzymes, hyaluronan synthase (HAS)1, 2, and 3. HA synthesis mediated by HAS3 promotes inflammation and is pathogenic in animal models of human lung and intestinal disease. Liver fi...

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Detalles Bibliográficos
Autores principales:	McCracken, Jennifer M., Jiang, Lu, Deshpande, Krutika T., O’Neil, Maura F., Pritchard, Michele T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818527/ https://www.ncbi.nlm.nih.gov/pubmed/27042213 http://dx.doi.org/10.1186/s13069-016-0041-5

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