Mitochondrial disorders in children: toward development of small‐molecule treatment strategies

This review presents our current understanding of the pathophysiology and potential treatment strategies with respect to mitochondrial disease in children. We focus on pathologies due to mutations in nuclear DNA‐encoded structural and assembly factors of the mitochondrial oxidative phosphorylation (...

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Detalles Bibliográficos
Autores principales: Koopman, Werner JH, Beyrath, Julien, Fung, Cheuk‐Wing, Koene, Saskia, Rodenburg, Richard J, Willems, Peter HGM, Smeitink, Jan AM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818752/
https://www.ncbi.nlm.nih.gov/pubmed/26951622
http://dx.doi.org/10.15252/emmm.201506131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818752/
https://www.ncbi.nlm.nih.gov/pubmed/26951622
http://dx.doi.org/10.15252/emmm.201506131

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