Topographic expression of the Hippo transducers TAZ and YAP in triple-negative breast cancer treated with neoadjuvant chemotherapy

BACKGROUND: The Hippo signaling acts as a tumor-suppressor pathway that negatively regulates TAZ and YAP. Increasing evidence supports the activation of TAZ and YAP in breast cancer. Moreover, the Hippo pathway is involved in the biology of non-neoplastic cells residing in the tumor microenvironment...

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Detalles Bibliográficos
Autores principales: Vici, Patrizia, Ercolani, Cristiana, Di Benedetto, Anna, Pizzuti, Laura, Di Lauro, Luigi, Sperati, Francesca, Terrenato, Irene, Gamucci, Teresa, Natoli, Clara, Di Filippo, Franco, Botti, Claudio, Barba, Maddalena, Mottolese, Marcella, De Maria, Ruggero, Maugeri-Saccà, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818869/
https://www.ncbi.nlm.nih.gov/pubmed/27039292
http://dx.doi.org/10.1186/s13046-016-0338-7

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