Reproducibility of Illumina platform deep sequencing errors allows accurate determination of DNA barcodes in cells

BACKGROUND: Next generation sequencing (NGS) of amplified DNA is a powerful tool to describe genetic heterogeneity within cell populations that can both be used to investigate the clonal structure of cell populations and to perform genetic lineage tracing. For applications in which both abundant and...

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Detalles Bibliográficos
Autores principales: Beltman, Joost B., Urbanus, Jos, Velds, Arno, van Rooij, Nienke, Rohr, Jan C., Naik, Shalin H., Schumacher, Ton N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818877/
https://www.ncbi.nlm.nih.gov/pubmed/27038897
http://dx.doi.org/10.1186/s12859-016-0999-4

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