miR-720 is a downstream target of an ADAM8-induced ERK signaling cascade that promotes the migratory and invasive phenotype of triple-negative breast cancer cells

BACKGROUND: ADAM8 (a disintegrin and metalloproteinase 8) protein promotes the invasive and metastatic phenotype of triple-negative breast cancer (TNBC) cells. High ADAM8 expression in breast cancer patients is an independent predictor of poor prognosis. Here, we investigated whether ADAM8 regulates...

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Detalles Bibliográficos
Autores principales: Das, Sonia G., Romagnoli, Mathilde, Mineva, Nora D., Barillé-Nion, Sophie, Jézéquel, Pascal, Campone, Mario, Sonenshein, Gail E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818899/
https://www.ncbi.nlm.nih.gov/pubmed/27039296
http://dx.doi.org/10.1186/s13058-016-0699-z

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