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A flexible tool to plot a genomic map for single nucleotide polymorphisms
BACKGROUND: Most genetic association studies use single-nucleotide polymorphisms (SNPs) as the research targets. However, resources to visualize the genomic map of candidate SNPs in a programming manner are limited. We have previously created an R package, mapsnp v0.1, to plot the genomic map for a...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818925/ https://www.ncbi.nlm.nih.gov/pubmed/27042203 http://dx.doi.org/10.1186/s13029-016-0052-z |
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author | Zhang, Fuquan |
author_facet | Zhang, Fuquan |
author_sort | Zhang, Fuquan |
collection | PubMed |
description | BACKGROUND: Most genetic association studies use single-nucleotide polymorphisms (SNPs) as the research targets. However, resources to visualize the genomic map of candidate SNPs in a programming manner are limited. We have previously created an R package, mapsnp v0.1, to plot the genomic map for a panel of SNPs within a genomic region of interest. It failed to work under the latest version of Gviz package. RESULTS: We updated the mapsnp package to keep up with the latest package environment and improved its functionality by adding more parameters to fine tune plotting outputs. CONCLUSIONS: The mapsnp package is a flexible software to visualize genomic map for SNPs, involving the relative chromosome location and the transcripts in the region. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13029-016-0052-z) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-4818925 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-48189252016-04-04 A flexible tool to plot a genomic map for single nucleotide polymorphisms Zhang, Fuquan Source Code Biol Med Software BACKGROUND: Most genetic association studies use single-nucleotide polymorphisms (SNPs) as the research targets. However, resources to visualize the genomic map of candidate SNPs in a programming manner are limited. We have previously created an R package, mapsnp v0.1, to plot the genomic map for a panel of SNPs within a genomic region of interest. It failed to work under the latest version of Gviz package. RESULTS: We updated the mapsnp package to keep up with the latest package environment and improved its functionality by adding more parameters to fine tune plotting outputs. CONCLUSIONS: The mapsnp package is a flexible software to visualize genomic map for SNPs, involving the relative chromosome location and the transcripts in the region. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13029-016-0052-z) contains supplementary material, which is available to authorized users. BioMed Central 2016-04-02 /pmc/articles/PMC4818925/ /pubmed/27042203 http://dx.doi.org/10.1186/s13029-016-0052-z Text en © Zhang. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Software Zhang, Fuquan A flexible tool to plot a genomic map for single nucleotide polymorphisms |
title | A flexible tool to plot a genomic map for single nucleotide polymorphisms |
title_full | A flexible tool to plot a genomic map for single nucleotide polymorphisms |
title_fullStr | A flexible tool to plot a genomic map for single nucleotide polymorphisms |
title_full_unstemmed | A flexible tool to plot a genomic map for single nucleotide polymorphisms |
title_short | A flexible tool to plot a genomic map for single nucleotide polymorphisms |
title_sort | flexible tool to plot a genomic map for single nucleotide polymorphisms |
topic | Software |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818925/ https://www.ncbi.nlm.nih.gov/pubmed/27042203 http://dx.doi.org/10.1186/s13029-016-0052-z |
work_keys_str_mv | AT zhangfuquan aflexibletooltoplotagenomicmapforsinglenucleotidepolymorphisms AT zhangfuquan flexibletooltoplotagenomicmapforsinglenucleotidepolymorphisms |