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A flexible tool to plot a genomic map for single nucleotide polymorphisms

BACKGROUND: Most genetic association studies use single-nucleotide polymorphisms (SNPs) as the research targets. However, resources to visualize the genomic map of candidate SNPs in a programming manner are limited. We have previously created an R package, mapsnp v0.1, to plot the genomic map for a...

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Detalles Bibliográficos
Autor principal: Zhang, Fuquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818925/
https://www.ncbi.nlm.nih.gov/pubmed/27042203
http://dx.doi.org/10.1186/s13029-016-0052-z
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author Zhang, Fuquan
author_facet Zhang, Fuquan
author_sort Zhang, Fuquan
collection PubMed
description BACKGROUND: Most genetic association studies use single-nucleotide polymorphisms (SNPs) as the research targets. However, resources to visualize the genomic map of candidate SNPs in a programming manner are limited. We have previously created an R package, mapsnp v0.1, to plot the genomic map for a panel of SNPs within a genomic region of interest. It failed to work under the latest version of Gviz package. RESULTS: We updated the mapsnp package to keep up with the latest package environment and improved its functionality by adding more parameters to fine tune plotting outputs. CONCLUSIONS: The mapsnp package is a flexible software to visualize genomic map for SNPs, involving the relative chromosome location and the transcripts in the region. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13029-016-0052-z) contains supplementary material, which is available to authorized users.
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spelling pubmed-48189252016-04-04 A flexible tool to plot a genomic map for single nucleotide polymorphisms Zhang, Fuquan Source Code Biol Med Software BACKGROUND: Most genetic association studies use single-nucleotide polymorphisms (SNPs) as the research targets. However, resources to visualize the genomic map of candidate SNPs in a programming manner are limited. We have previously created an R package, mapsnp v0.1, to plot the genomic map for a panel of SNPs within a genomic region of interest. It failed to work under the latest version of Gviz package. RESULTS: We updated the mapsnp package to keep up with the latest package environment and improved its functionality by adding more parameters to fine tune plotting outputs. CONCLUSIONS: The mapsnp package is a flexible software to visualize genomic map for SNPs, involving the relative chromosome location and the transcripts in the region. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13029-016-0052-z) contains supplementary material, which is available to authorized users. BioMed Central 2016-04-02 /pmc/articles/PMC4818925/ /pubmed/27042203 http://dx.doi.org/10.1186/s13029-016-0052-z Text en © Zhang. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Software
Zhang, Fuquan
A flexible tool to plot a genomic map for single nucleotide polymorphisms
title A flexible tool to plot a genomic map for single nucleotide polymorphisms
title_full A flexible tool to plot a genomic map for single nucleotide polymorphisms
title_fullStr A flexible tool to plot a genomic map for single nucleotide polymorphisms
title_full_unstemmed A flexible tool to plot a genomic map for single nucleotide polymorphisms
title_short A flexible tool to plot a genomic map for single nucleotide polymorphisms
title_sort flexible tool to plot a genomic map for single nucleotide polymorphisms
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818925/
https://www.ncbi.nlm.nih.gov/pubmed/27042203
http://dx.doi.org/10.1186/s13029-016-0052-z
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