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Repurposing an orally available drug for the treatment of geographic atrophy

PURPOSE: Chronic oxidative stress and subacute inflammation have been implicated as causes of age-related macular degeneration (AMD). In this study, we tested whether an orally available 5-OH-tryptamine (5HT) 1a receptor agonist, xaliproden, could protect against retinal pigment epithelium (RPE) cel...

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Detalles Bibliográficos
Autores principales:	Ahmed, Chulbul M., Biswal, Manas R., Li, Hong, Han, Pingyang, Ildefonso, Cristhian J., Lewin, Alfred S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Vision 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818958/ https://www.ncbi.nlm.nih.gov/pubmed/27110092

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