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Candidate SNP Markers of Gender-Biased Autoimmune Complications of Monogenic Diseases Are Predicted by a Significant Change in the Affinity of TATA-Binding Protein for Human Gene Promoters

Some variations of human genome [for example, single nucleotide polymorphisms (SNPs)] are markers of hereditary diseases and drug responses. Analysis of them can help to improve treatment. Computer-based analysis of millions of SNPs in the 1000 Genomes project makes a search for SNP markers more tar...

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Detalles Bibliográficos
Autores principales: Ponomarenko, Mikhail P., Arkova, Olga, Rasskazov, Dmitry, Ponomarenko, Petr, Savinkova, Ludmila, Kolchanov, Nikolay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819121/
https://www.ncbi.nlm.nih.gov/pubmed/27092142
http://dx.doi.org/10.3389/fimmu.2016.00130