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Gastritis and Gastric Ulcers in Working Dogs
Gastritis and gastric ulcers are an important cause of morbidity and mortality in canine athletes. Although the majority of scientific work on this condition has been performed in ultraendurance racing sled dogs, this condition has been identified in other canine athletes, including sled dogs compet...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819149/ https://www.ncbi.nlm.nih.gov/pubmed/27092307 http://dx.doi.org/10.3389/fvets.2016.00030 |
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author | Davis, Michael S. Williamson, Katherine K. |
author_facet | Davis, Michael S. Williamson, Katherine K. |
author_sort | Davis, Michael S. |
collection | PubMed |
description | Gastritis and gastric ulcers are an important cause of morbidity and mortality in canine athletes. Although the majority of scientific work on this condition has been performed in ultraendurance racing sled dogs, this condition has been identified in other canine athletes, including sled dogs competing in shorter events and dogs performing off-leash explosive detection duties. The cause of the syndrome is unknown, but current hypotheses propose a link between exercise-induced hyperthermia and loss of gastric mucosal barrier function as an early event in the pathogenesis. Treatment is focused on prevention of clinical disease using acid secretion inhibitors, such as omeprazole, which has excellent efficacy in controlled clinical studies. |
format | Online Article Text |
id | pubmed-4819149 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-48191492016-04-18 Gastritis and Gastric Ulcers in Working Dogs Davis, Michael S. Williamson, Katherine K. Front Vet Sci Veterinary Science Gastritis and gastric ulcers are an important cause of morbidity and mortality in canine athletes. Although the majority of scientific work on this condition has been performed in ultraendurance racing sled dogs, this condition has been identified in other canine athletes, including sled dogs competing in shorter events and dogs performing off-leash explosive detection duties. The cause of the syndrome is unknown, but current hypotheses propose a link between exercise-induced hyperthermia and loss of gastric mucosal barrier function as an early event in the pathogenesis. Treatment is focused on prevention of clinical disease using acid secretion inhibitors, such as omeprazole, which has excellent efficacy in controlled clinical studies. Frontiers Media S.A. 2016-04-04 /pmc/articles/PMC4819149/ /pubmed/27092307 http://dx.doi.org/10.3389/fvets.2016.00030 Text en Copyright © 2016 Davis and Williamson. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Veterinary Science Davis, Michael S. Williamson, Katherine K. Gastritis and Gastric Ulcers in Working Dogs |
title | Gastritis and Gastric Ulcers in Working Dogs |
title_full | Gastritis and Gastric Ulcers in Working Dogs |
title_fullStr | Gastritis and Gastric Ulcers in Working Dogs |
title_full_unstemmed | Gastritis and Gastric Ulcers in Working Dogs |
title_short | Gastritis and Gastric Ulcers in Working Dogs |
title_sort | gastritis and gastric ulcers in working dogs |
topic | Veterinary Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819149/ https://www.ncbi.nlm.nih.gov/pubmed/27092307 http://dx.doi.org/10.3389/fvets.2016.00030 |
work_keys_str_mv | AT davismichaels gastritisandgastriculcersinworkingdogs AT williamsonkatherinek gastritisandgastriculcersinworkingdogs |