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Neural Progenitors Adopt Specific Identities by Directly Repressing All Alternative Progenitor Transcriptional Programs

In the vertebrate neural tube, a morphogen-induced transcriptional network produces multiple molecularly distinct progenitor domains, each generating different neuronal subtypes. Using an in vitro differentiation system, we defined gene expression signatures of distinct progenitor populations and id...

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Detalles Bibliográficos
Autores principales: Kutejova, Eva, Sasai, Noriaki, Shah, Ankita, Gouti, Mina, Briscoe, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819439/
https://www.ncbi.nlm.nih.gov/pubmed/26972603
http://dx.doi.org/10.1016/j.devcel.2016.02.013