In Crystallo Capture of a Covalent Intermediate in the UDP-Galactopyranose Mutase Reaction

[Image: see text] UDP-galactopyranose mutase (UGM) plays an essential role in galactofuranose biosynthesis in pathogens by catalyzing the conversion of UDP-galactopyranose to UDP-galactofuranose. Here we report the first crystal structure of a covalent intermediate in the UGM reaction. The 2.3 Å res...

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Detalles Bibliográficos
Autores principales: Mehra-Chaudhary, Ritcha, Dai, Yumin, Sobrado, Pablo, Tanner, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819441/
https://www.ncbi.nlm.nih.gov/pubmed/26836146
http://dx.doi.org/10.1021/acs.biochem.6b00035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819441/
https://www.ncbi.nlm.nih.gov/pubmed/26836146
http://dx.doi.org/10.1021/acs.biochem.6b00035

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