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In Crystallo Capture of a Covalent Intermediate in the UDP-Galactopyranose Mutase Reaction
[Image: see text] UDP-galactopyranose mutase (UGM) plays an essential role in galactofuranose biosynthesis in pathogens by catalyzing the conversion of UDP-galactopyranose to UDP-galactofuranose. Here we report the first crystal structure of a covalent intermediate in the UGM reaction. The 2.3 Å res...
Autores principales: | Mehra-Chaudhary, Ritcha, Dai, Yumin, Sobrado, Pablo, Tanner, John J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2016
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819441/ https://www.ncbi.nlm.nih.gov/pubmed/26836146 http://dx.doi.org/10.1021/acs.biochem.6b00035 |
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