Suppression of the senescence-associated secretory phenotype (SASP) in human fibroblasts using small molecule inhibitors of p38 MAP kinase and MK2

Senescent cells show an altered secretome profile termed the senescence-associated secretory phenotype (SASP). There is an increasing body of evidence that suggests that the accumulation of SASP-positive senescent cells in humans is partially causal in the observed shift to a low-level pro-inflammat...

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Detalles Bibliográficos
Autores principales: Alimbetov, Dauren, Davis, Terence, Brook, Amy J. C., Cox, Lynne S., Faragher, Richard G. A., Nurgozhin, Talgat, Zhumadilov, Zhaxybay, Kipling, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819486/
https://www.ncbi.nlm.nih.gov/pubmed/26400758
http://dx.doi.org/10.1007/s10522-015-9610-z

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