Total Synthesis of (−)-Mandelalide A Exploiting Anion Relay Chemistry (ARC): Identification of a Type II ARC/CuCN Cross-Coupling Protocol

[Image: see text] Anion relay chemistry (ARC), an effective, multicomponent union tactic, was successfully employed for the total synthesis of the highly cytotoxic marine macrolide (−)-mandelalide A (1). The northern hemisphere was constructed via a new type II ARC/CuCN cross-coupling tactic, while...

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Detalles Bibliográficos
Autores principales: Nguyen, Minh H., Imanishi, Masashi, Kurogi, Taichi, Smith, Amos B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819492/
https://www.ncbi.nlm.nih.gov/pubmed/26954306
http://dx.doi.org/10.1021/jacs.6b01731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819492/
https://www.ncbi.nlm.nih.gov/pubmed/26954306
http://dx.doi.org/10.1021/jacs.6b01731

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