The differential effects of metronomic gemcitabine and antiangiogenic treatment in patient-derived xenografts of pancreatic cancer: treatment effects on metabolism, vascular function, cell proliferation, and tumor growth

BACKGROUND: Metronomic chemotherapy has shown promising activity against solid tumors and is believed to act in an antiangiogenic manner. The current study describes and quantifies the therapeutic efficacy, and mode of activity, of metronomic gemcitabine and a dedicated antiangiogenic agent (DC101)...

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Detalles Bibliográficos
Autores principales: Yapp, Donald T., Wong, May Q., Kyle, Alastair H., Valdez, Shannon M., Tso, Jenny, Yung, Andrew, Kozlowski, Piotr, Owen, David A., Buczkowski, Andrzej K., Chung, Stephen W., Scudamore, Charles H., Minchinton, Andrew I., Ng, Sylvia S. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819514/
https://www.ncbi.nlm.nih.gov/pubmed/26961182
http://dx.doi.org/10.1007/s10456-016-9503-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819514/
https://www.ncbi.nlm.nih.gov/pubmed/26961182
http://dx.doi.org/10.1007/s10456-016-9503-z

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