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The application of local hypobaric pressure — A novel means to enhance macromolecule entry into the skin
The local application of controlled hypobaric stress represents a novel means to facilitate drug delivery into the skin. The aims of this work were to understand how hypobaric stress modified the properties of the skin and assess if this penetration enhancement strategy could improve the percutaneou...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Publishers
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819566/ https://www.ncbi.nlm.nih.gov/pubmed/26829103 http://dx.doi.org/10.1016/j.jconrel.2016.01.052 |