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Clinical Application of High-Resolution Computed Tomographic Imaging Features of Community-Acquired Pneumonia

BACKGROUND: This article discusses the value of high-resolution computed tomography (HRCT) in the diagnosis and treatment of pulmonary infections. Lung infection caused by pathogens is an important cause of death. Traditional methods to treat lung infection involved empirical antibiotic therapy. Thi...

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Autores principales: Nie, Yunqiang, Li, Cuiyun, Zhang, Jingling, Wang, Hui, Han, Ping, Lv, Xin, Xu, Xinyi, Guo, Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819687/
https://www.ncbi.nlm.nih.gov/pubmed/27031210
http://dx.doi.org/10.12659/MSM.895638
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author Nie, Yunqiang
Li, Cuiyun
Zhang, Jingling
Wang, Hui
Han, Ping
Lv, Xin
Xu, Xinyi
Guo, Miao
author_facet Nie, Yunqiang
Li, Cuiyun
Zhang, Jingling
Wang, Hui
Han, Ping
Lv, Xin
Xu, Xinyi
Guo, Miao
author_sort Nie, Yunqiang
collection PubMed
description BACKGROUND: This article discusses the value of high-resolution computed tomography (HRCT) in the diagnosis and treatment of pulmonary infections. Lung infection caused by pathogens is an important cause of death. Traditional methods to treat lung infection involved empirical antibiotic therapy. Thin-slice CT scanning is widely used in the clinical setting, and HRCT scan can very clearly show alveolar and bronchiolar involvement of infection. MATERIAL/METHODS: In total, 178 patients with community-acquired pneumonia (CAP) were enrolled. All the patients underwent CT scan, qualified sputum, and blood samples for culture or immunological biochemical tests. CT imaging features, pathogenic bacteria, and treatment results were used for statistical analysis. RESULTS: In 77 patients with lobar consolidation, the rate of detection was 43.26% (77/178), and in 101 patients with lobular pneumonia it was 56.74% (101/178). In 51 patients, pathogenic bacteria were detected (28.65%, 51/178). Sixteen of 33 patients detected with bacteria had cavities (48.5%, 16/33) and 35 of 145 patients detected with bacteria had no cavities (24.1%, 35/145). The difference between the 2 groups was statistically significant (χ(2)=7.795, P=0.005). According to the pathogenic bacteria, 38 patients were cured (74.51%, 38/51), and according to the CT imaging features 81 patients were cured (71.05%, 81/114). No statistically significant difference was found between them (χ(2)=0.209, P=0.647). CONCLUSIONS: Treatment effect of CAP based on HRCT findings is not inferior to treatment effect guided by microbial characterization.
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spelling pubmed-48196872016-04-14 Clinical Application of High-Resolution Computed Tomographic Imaging Features of Community-Acquired Pneumonia Nie, Yunqiang Li, Cuiyun Zhang, Jingling Wang, Hui Han, Ping Lv, Xin Xu, Xinyi Guo, Miao Med Sci Monit Clinical Research BACKGROUND: This article discusses the value of high-resolution computed tomography (HRCT) in the diagnosis and treatment of pulmonary infections. Lung infection caused by pathogens is an important cause of death. Traditional methods to treat lung infection involved empirical antibiotic therapy. Thin-slice CT scanning is widely used in the clinical setting, and HRCT scan can very clearly show alveolar and bronchiolar involvement of infection. MATERIAL/METHODS: In total, 178 patients with community-acquired pneumonia (CAP) were enrolled. All the patients underwent CT scan, qualified sputum, and blood samples for culture or immunological biochemical tests. CT imaging features, pathogenic bacteria, and treatment results were used for statistical analysis. RESULTS: In 77 patients with lobar consolidation, the rate of detection was 43.26% (77/178), and in 101 patients with lobular pneumonia it was 56.74% (101/178). In 51 patients, pathogenic bacteria were detected (28.65%, 51/178). Sixteen of 33 patients detected with bacteria had cavities (48.5%, 16/33) and 35 of 145 patients detected with bacteria had no cavities (24.1%, 35/145). The difference between the 2 groups was statistically significant (χ(2)=7.795, P=0.005). According to the pathogenic bacteria, 38 patients were cured (74.51%, 38/51), and according to the CT imaging features 81 patients were cured (71.05%, 81/114). No statistically significant difference was found between them (χ(2)=0.209, P=0.647). CONCLUSIONS: Treatment effect of CAP based on HRCT findings is not inferior to treatment effect guided by microbial characterization. International Scientific Literature, Inc. 2016-03-31 /pmc/articles/PMC4819687/ /pubmed/27031210 http://dx.doi.org/10.12659/MSM.895638 Text en © Med Sci Monit, 2016 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License
spellingShingle Clinical Research
Nie, Yunqiang
Li, Cuiyun
Zhang, Jingling
Wang, Hui
Han, Ping
Lv, Xin
Xu, Xinyi
Guo, Miao
Clinical Application of High-Resolution Computed Tomographic Imaging Features of Community-Acquired Pneumonia
title Clinical Application of High-Resolution Computed Tomographic Imaging Features of Community-Acquired Pneumonia
title_full Clinical Application of High-Resolution Computed Tomographic Imaging Features of Community-Acquired Pneumonia
title_fullStr Clinical Application of High-Resolution Computed Tomographic Imaging Features of Community-Acquired Pneumonia
title_full_unstemmed Clinical Application of High-Resolution Computed Tomographic Imaging Features of Community-Acquired Pneumonia
title_short Clinical Application of High-Resolution Computed Tomographic Imaging Features of Community-Acquired Pneumonia
title_sort clinical application of high-resolution computed tomographic imaging features of community-acquired pneumonia
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819687/
https://www.ncbi.nlm.nih.gov/pubmed/27031210
http://dx.doi.org/10.12659/MSM.895638
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