Cargando…

Inhibition of GSK-3β Alleviates Collagen II-Induced Rheumatoid Arthritis in Rats

BACKGROUND: Glycogen synthase kinase-3β (GSK-3β) inhibitor is a serine/threonine kinase with an inhibitory role in glycogen synthesis, which is essential in inflammatory and immunological diseases. The purpose of our study was to determine if TDZD-8 can alleviate collagen II-induced rheumatoid arthr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Haiyan, Liu, Jun, Zeng, Jiashun, Hu, Bailong, Fang, Xiuyi, Li, Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2016
Materias:	Animal Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819688/ https://www.ncbi.nlm.nih.gov/pubmed/27029564 http://dx.doi.org/10.12659/MSM.897739

Ejemplares similares

Treatment of Type II Collagen-Induced Rat Rheumatoid Arthritis Model by Interleukin 10 (IL10)-Mesenchymal Stem Cells (BMSCs)
por: Tian, Shuai, et al.
Publicado: (2019)

Phosphorylated Glycogen Synthase Kinase-3β (GSK-3β) Improves Cognition in Rats with Diabetes-Associated Cognitive Decline
por: Ke, Boxi, et al.
Publicado: (2019)

Substance P Inhibits the Collagen Synthesis of Rat Myocardial Fibroblasts Induced by Ang II
por: Yang, Zhiyong, et al.
Publicado: (2016)

Salvianolic Acid B Suppresses Inflammatory Mediator Levels by Downregulating NF-κB in a Rat Model of Rheumatoid Arthritis
por: Xia, Zeng-Bing, et al.
Publicado: (2018)

Protective Effects of Ischemic Postconditioning on Livers in Rats with Limb Ischemia-Reperfusion via Glycogen Synthase Kinase 3 beta (GSK-3β)/Fyn/Nuclear Receptor-Erythroid-2-Related Factor (Nrf2) Pathway
por: Niu, Qibing, et al.
Publicado: (2020)

High-Performance Liquid Chromatography (HPLC) Quantification of Liposome-Delivered Doxorubicin in Arthritic Joints of Collagen-Induced Arthritis Rats
por: Niu, Hongqing, et al.
Publicado: (2017)

Norepinephrine Inhibits Th17 Cells via β2-Adrenergic Receptor (β2-AR) Signaling in a Mouse Model of Rheumatoid Arthritis
por: Liu, Yan, et al.
Publicado: (2018)

Effect of Tendon Stem Cells in Chitosan/β-Glycerophosphate/Collagen Hydrogel on Achilles Tendon Healing in a Rat Model
por: Yang, Zhijin, et al.
Publicado: (2017)

Retinoic Acid-Platinum (II) Complex [RT-Pt(II)] Protects Against Rheumatoid Arthritis in Mice via MEK/Nuclear Factor kappa B (NF-κB) Pathway Downregulation
por: Cui, Ziqiang, et al.
Publicado: (2020)

Effects and Mechanism of SO(2) Inhalation on Rat Myocardial Collagen Fibers
por: Chen, Ping, et al.
Publicado: (2018)

Value of Contrast-Enhanced Ultrasonography in Evaluating Rheumatoid Arthritis: Preliminary Research Based on an Animal Model
por: Gong, Yiran, et al.
Publicado: (2021)

17β-Estradiol Protects Rat Annulus Fibrosus Cells Against Apoptosis via α(1) Integrin-Mediated Adhesion to Type I Collagen: An In-vitro Study
por: Zhao, Chun-Ming, et al.
Publicado: (2016)

Recombinant Osteopontin Improves Neurological Functional Recovery and Protects Against Apoptosis via PI3K/Akt/GSK-3β Pathway Following Intracerebral Hemorrhage
por: Zhang, Wenqian, et al.
Publicado: (2018)

Apigenin Alleviates Myocardial Reperfusion Injury in Rats by Downregulating miR-15b
por: Wang, PeiPei, et al.
Publicado: (2019)

Nuclear Factor kappa B (NF-κB) Targeted Self-Assembled Nanoparticles Loaded with Methotrexate for Treatment of Rheumatoid Arthritis
por: Li, Xiong, et al.
Publicado: (2019)

Rhubarb and Astragalus Capsule Attenuates Renal Interstitial Fibrosis in Rats with Unilateral Ureteral Obstruction by Alleviating Apoptosis through Regulating Transforming Growth Factor beta1 (TGF-β1)/p38 Mitogen-Activated Protein Kinases (p38 MAPK) Pathway
por: Zeng, Xian, et al.
Publicado: (2020)

Hypertonic Saline Alleviates Brain Edema After Traumatic Brain Injury via Downregulation of Aquaporin 4 in Rats
por: Yin, Jian, et al.
Publicado: (2018)

Dihydrotanshinone I Alleviates Spinal Cord Injury via Suppressing Inflammatory Response, Oxidative Stress and Apoptosis in Rats
por: Yu, Liuqian, et al.
Publicado: (2020)

Baicalin Ameliorates Collagen-Induced Arthritis Through the Suppression of Janus Kinase 1 (JAK1)/Signal Transducer and Activator of Transcription 3 (STAT3) Signaling in Mice
por: Wang, Chunxiao, et al.
Publicado: (2018)

Acupuncture Administration Improves Cognitive Functions and Alleviates Inflammation and Nuclear Damage by Regulating Phosphatidylinositol 3 Kinase (PI3K)/Phosphoinositol-Dependent Kinase 1 (PDK1)/Novel Protein Kinase C (nPKC)/Rac 1 Signaling Pathway in Senescence-Accelerated Prone 8 (SAM-P8) Mice
por: Li, Guomin, et al.
Publicado: (2019)

Protective Effect of Pinitol Against Inflammatory Mediators of Rheumatoid Arthritis via Inhibition of Protein Tyrosine Phosphatase Non-Receptor Type 22 (PTPN22)
por: Zheng, Kewen, et al.
Publicado: (2017)

Catalpol Attenuates IL-1β Induced Matrix Catabolism, Apoptosis and Inflammation in Rat Chondrocytes and Inhibits Cartilage Degeneration
por: Zeng, Yun-fu, et al.
Publicado: (2019)

Tetrahydropyrimidines, ZL-5015 Alleviated Lipopolysaccharide (LPS)-Induced Acute Pneumonia in Rats by Activating the NRF-2/HO-1 Pathway
por: Sun, Wei, et al.
Publicado: (2020)

Intermedin 1-53 Inhibits Myocardial Fibrosis in Rats by Down-Regulating Transforming Growth Factor-β
por: Fang, Jian, et al.
Publicado: (2017)

Activation of TGR5 alleviates inflammation in rheumatoid arthritis peripheral blood mononuclear cells and in mice with collagen II-induced arthritis
por: Li, Zhe-Yong, et al.
Publicado: (2019)

Autoimmunity to citrullinated type II collagen in rheumatoid arthritis
por: Yoshida, Mamoru, et al.
Publicado: (2006)

Therapeutic Effect of Nile Tilapia Type II Collagen on Rigidity in CD8(+) Cells by Alleviating Inflammation and Rheumatoid Arthritis in Rats by Oral Tolerance
por: Hou, Chunyu, et al.
Publicado: (2022)

Impact of β-Adrenoceptor Blockade on Systemic Inflammation and Coagulation Disturbances in Rats with Acute Traumatic Coagulopathy
por: Xu, Lin, et al.
Publicado: (2015)

Effects of (12)C(6+) Heavy Ion Radiation on Dendritic Cells Function
por: Zhang, Pei, et al.
Publicado: (2018)

Effect of Urinary Kallidinogenase on Transforming Growth Factor-β(1) and High-Sensitivity C-Reactive Protein Expression in Rat Focal Cerebral Ischemic Injury
por: Dong, Ting-Fang, et al.
Publicado: (2016)

Jintiange Capsule Alleviates Rheumatoid Arthritis and Reverses Changes of Serum Metabolic Profile in Collagen-Induced Arthritic Rats
por: Wang, Xiaoyan, et al.
Publicado: (2021)

Human β-Defensin-2 Improves Hyperoxia-Induced Lung Structural and Functional Injury in Neonatal Rats
por: Sun, Yuanyuan, et al.
Publicado: (2019)

Impact of Gentamicin-Impregnated Collagen on the Intra-Abdominal Adhesions and Integrity of Colonic Anastomosis: An Experimental Study
por: Oruç, Esin Ertürer, et al.
Publicado: (2021)

Cardioprotective Effects of Malvidin Against Isoproterenol-Induced Myocardial Infarction in Rats: A Mechanistic Study
por: Wei, Hui, et al.
Publicado: (2017)

TGF-β1/Smad3 Signaling Pathway Suppresses Cell Apoptosis in Cerebral Ischemic Stroke Rats
por: Zhu, Haiping, et al.
Publicado: (2017)

Polydatin Alleviates Radiation-Induced Testes Injury by Scavenging ROS and Inhibiting Apoptosis Pathways
por: Ma, Yan, et al.
Publicado: (2018)

Emodin Alleviates the Airway Inflammation of Cough Variant Asthma in Mice by Regulating the Notch Pathway
por: Hua, Shu, et al.
Publicado: (2019)

The Role of Melatonin in Electroacupuncture Alleviating Lung Injury Induced by Limb Ischemia-Reperfusion in Rabbits
por: Dong, Shu-an, et al.
Publicado: (2020)

Treatment Efficacy of NGF Nanoparticles Combining Neural Stem Cell Transplantation on Alzheimer’s Disease Model Rats
por: Chen, Yan, et al.
Publicado: (2015)

Involvement of p53, p21, and Caspase-3 in Apoptosis of Coronary Artery Smooth Muscle Cells in a Kawasaki Vasculitis Mouse Model
por: Deng, Minghong, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5pasdo6ncjdfo4jieud7orirr5