The epidemiology of rotavirus disease in under-five-year-old children hospitalized with acute diarrhea in central Uganda, 2012-2013

A cross-sectional study was undertaken during 2012-2013 to determine the prevalence, strains and factors associated with rotavirus infection among under-5-year-old children hospitalized with acute diarrhea in Uganda. Rotaviruses were detected in 37 % (263/712) of the children. The most prevalent str...

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Autores principales: Bwogi, Josephine, Malamba, Samuel, Kigozi, Brian, Namuwulya, Prossy, Tushabe, Phionah, Kiguli, Sarah, Byarugaba, Denis Karuhize, Desselberger, Ulrich, Iturriza-Gomara, Miren, Karamagi, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2016
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819735/
https://www.ncbi.nlm.nih.gov/pubmed/26724820
http://dx.doi.org/10.1007/s00705-015-2742-2
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author Bwogi, Josephine
Malamba, Samuel
Kigozi, Brian
Namuwulya, Prossy
Tushabe, Phionah
Kiguli, Sarah
Byarugaba, Denis Karuhize
Desselberger, Ulrich
Iturriza-Gomara, Miren
Karamagi, Charles
author_facet Bwogi, Josephine
Malamba, Samuel
Kigozi, Brian
Namuwulya, Prossy
Tushabe, Phionah
Kiguli, Sarah
Byarugaba, Denis Karuhize
Desselberger, Ulrich
Iturriza-Gomara, Miren
Karamagi, Charles
author_sort Bwogi, Josephine
collection PubMed
description A cross-sectional study was undertaken during 2012-2013 to determine the prevalence, strains and factors associated with rotavirus infection among under-5-year-old children hospitalized with acute diarrhea in Uganda. Rotaviruses were detected in 37 % (263/712) of the children. The most prevalent strains were G9P[8] (27 %, 55/204) and G12P[4] (18.6 %, 38/204). Mixed infections were detected in 22.5 % (46/204) of the children. The study suggests that consumption of raw vegetables (OR = 1.45, 95 % CI = 1.03-2.03) and family ownership of dogs (OR = 1.9, 95 % CI = 1.04-3.75) increases the risk of rotavirus infection. The study findings will be used to assess the impact of RV vaccination in Uganda.
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spelling pubmed-48197352016-04-10 The epidemiology of rotavirus disease in under-five-year-old children hospitalized with acute diarrhea in central Uganda, 2012-2013 Bwogi, Josephine Malamba, Samuel Kigozi, Brian Namuwulya, Prossy Tushabe, Phionah Kiguli, Sarah Byarugaba, Denis Karuhize Desselberger, Ulrich Iturriza-Gomara, Miren Karamagi, Charles Arch Virol Brief Report A cross-sectional study was undertaken during 2012-2013 to determine the prevalence, strains and factors associated with rotavirus infection among under-5-year-old children hospitalized with acute diarrhea in Uganda. Rotaviruses were detected in 37 % (263/712) of the children. The most prevalent strains were G9P[8] (27 %, 55/204) and G12P[4] (18.6 %, 38/204). Mixed infections were detected in 22.5 % (46/204) of the children. The study suggests that consumption of raw vegetables (OR = 1.45, 95 % CI = 1.03-2.03) and family ownership of dogs (OR = 1.9, 95 % CI = 1.04-3.75) increases the risk of rotavirus infection. The study findings will be used to assess the impact of RV vaccination in Uganda. Springer Vienna 2016-01-02 2016 /pmc/articles/PMC4819735/ /pubmed/26724820 http://dx.doi.org/10.1007/s00705-015-2742-2 Text en © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Brief Report
Bwogi, Josephine
Malamba, Samuel
Kigozi, Brian
Namuwulya, Prossy
Tushabe, Phionah
Kiguli, Sarah
Byarugaba, Denis Karuhize
Desselberger, Ulrich
Iturriza-Gomara, Miren
Karamagi, Charles
The epidemiology of rotavirus disease in under-five-year-old children hospitalized with acute diarrhea in central Uganda, 2012-2013
title The epidemiology of rotavirus disease in under-five-year-old children hospitalized with acute diarrhea in central Uganda, 2012-2013
title_full The epidemiology of rotavirus disease in under-five-year-old children hospitalized with acute diarrhea in central Uganda, 2012-2013
title_fullStr The epidemiology of rotavirus disease in under-five-year-old children hospitalized with acute diarrhea in central Uganda, 2012-2013
title_full_unstemmed The epidemiology of rotavirus disease in under-five-year-old children hospitalized with acute diarrhea in central Uganda, 2012-2013
title_short The epidemiology of rotavirus disease in under-five-year-old children hospitalized with acute diarrhea in central Uganda, 2012-2013
title_sort epidemiology of rotavirus disease in under-five-year-old children hospitalized with acute diarrhea in central uganda, 2012-2013
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819735/
https://www.ncbi.nlm.nih.gov/pubmed/26724820
http://dx.doi.org/10.1007/s00705-015-2742-2
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