Multiple viral introductions: molecular characterization of influenza B virus in Wenzhou, Zhejiang, China, from 2011 to 2014 based on hemagglutinin and neuraminidase genes

Influenza B virus is a major causative agent of respiratory disease in humans. Our study of an outbreak of influenza B virus in Wenzhou from 2011 to 2014 revealed that 163 (5.58 %) of 2921 samples were influenza B positive. Sequencing of the hemagglutinin and neuraminidase genes showed substitutions...

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Autores principales: Chen, Dong, Wen, Xiaohong, Sun, Yi, Mao, Haiyan, Zhang, Yanjun, Chen, Yin, Wang, Xinying, Sun, Baochang, Wang, Xin, Zhang, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2016
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819752/
https://www.ncbi.nlm.nih.gov/pubmed/26724821
http://dx.doi.org/10.1007/s00705-015-2721-7
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author Chen, Dong
Wen, Xiaohong
Sun, Yi
Mao, Haiyan
Zhang, Yanjun
Chen, Yin
Wang, Xinying
Sun, Baochang
Wang, Xin
Zhang, Xiaoming
author_facet Chen, Dong
Wen, Xiaohong
Sun, Yi
Mao, Haiyan
Zhang, Yanjun
Chen, Yin
Wang, Xinying
Sun, Baochang
Wang, Xin
Zhang, Xiaoming
author_sort Chen, Dong
collection PubMed
description Influenza B virus is a major causative agent of respiratory disease in humans. Our study of an outbreak of influenza B virus in Wenzhou from 2011 to 2014 revealed that 163 (5.58 %) of 2921 samples were influenza B positive. Sequencing of the hemagglutinin and neuraminidase genes showed substitutions at the amino acid level. Phylogenetic analysis revealed co-circulation of the B/Victoria and B/Yamagata lineages in the Wenzhou area from 2011 to 2014. Multiple viral introductions from both Chinese and international sources played important roles in endemic co-circulation and transmission in coastal southeastern China. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00705-015-2721-7) contains supplementary material, which is available to authorized users.
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spelling pubmed-48197522016-04-10 Multiple viral introductions: molecular characterization of influenza B virus in Wenzhou, Zhejiang, China, from 2011 to 2014 based on hemagglutinin and neuraminidase genes Chen, Dong Wen, Xiaohong Sun, Yi Mao, Haiyan Zhang, Yanjun Chen, Yin Wang, Xinying Sun, Baochang Wang, Xin Zhang, Xiaoming Arch Virol Brief Report Influenza B virus is a major causative agent of respiratory disease in humans. Our study of an outbreak of influenza B virus in Wenzhou from 2011 to 2014 revealed that 163 (5.58 %) of 2921 samples were influenza B positive. Sequencing of the hemagglutinin and neuraminidase genes showed substitutions at the amino acid level. Phylogenetic analysis revealed co-circulation of the B/Victoria and B/Yamagata lineages in the Wenzhou area from 2011 to 2014. Multiple viral introductions from both Chinese and international sources played important roles in endemic co-circulation and transmission in coastal southeastern China. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00705-015-2721-7) contains supplementary material, which is available to authorized users. Springer Vienna 2016-01-02 2016 /pmc/articles/PMC4819752/ /pubmed/26724821 http://dx.doi.org/10.1007/s00705-015-2721-7 Text en © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Brief Report
Chen, Dong
Wen, Xiaohong
Sun, Yi
Mao, Haiyan
Zhang, Yanjun
Chen, Yin
Wang, Xinying
Sun, Baochang
Wang, Xin
Zhang, Xiaoming
Multiple viral introductions: molecular characterization of influenza B virus in Wenzhou, Zhejiang, China, from 2011 to 2014 based on hemagglutinin and neuraminidase genes
title Multiple viral introductions: molecular characterization of influenza B virus in Wenzhou, Zhejiang, China, from 2011 to 2014 based on hemagglutinin and neuraminidase genes
title_full Multiple viral introductions: molecular characterization of influenza B virus in Wenzhou, Zhejiang, China, from 2011 to 2014 based on hemagglutinin and neuraminidase genes
title_fullStr Multiple viral introductions: molecular characterization of influenza B virus in Wenzhou, Zhejiang, China, from 2011 to 2014 based on hemagglutinin and neuraminidase genes
title_full_unstemmed Multiple viral introductions: molecular characterization of influenza B virus in Wenzhou, Zhejiang, China, from 2011 to 2014 based on hemagglutinin and neuraminidase genes
title_short Multiple viral introductions: molecular characterization of influenza B virus in Wenzhou, Zhejiang, China, from 2011 to 2014 based on hemagglutinin and neuraminidase genes
title_sort multiple viral introductions: molecular characterization of influenza b virus in wenzhou, zhejiang, china, from 2011 to 2014 based on hemagglutinin and neuraminidase genes
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819752/
https://www.ncbi.nlm.nih.gov/pubmed/26724821
http://dx.doi.org/10.1007/s00705-015-2721-7
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