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Towards a compendium of essential genes – From model organisms to synthetic lethality in cancer cells
Essential genes are defined by their requirement to sustain life in cells or whole organisms. The systematic identification of essential gene sets not only allows insights into the fundamental building blocks of life, but may also provide novel therapeutic targets in oncology. The discovery of essen...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819810/ https://www.ncbi.nlm.nih.gov/pubmed/26627871 http://dx.doi.org/10.3109/10409238.2015.1117053 |