CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling

Innate immune signaling relies on the deposition of non-degradative polyubiquitin at receptor-signaling complexes, but how these ubiquitin modifications are regulated by deubiquitinases remains incompletely understood. Met1-linked ubiquitin (Met1-Ub) is assembled by the linear ubiquitin assembly com...

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Detalles Bibliográficos
Autores principales: Hrdinka, Matous, Fiil, Berthe Katrine, Zucca, Mattia, Leske, Derek, Bagola, Katrin, Yabal, Monica, Elliott, Paul R., Damgaard, Rune Busk, Komander, David, Jost, Philipp J., Gyrd-Hansen, Mads
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819907/
https://www.ncbi.nlm.nih.gov/pubmed/26997266
http://dx.doi.org/10.1016/j.celrep.2016.02.062

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