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Maintaining memory of silencing at imprinted differentially methylated regions

Imprinted genes are an exceptional cluster of genes which are expressed in a parent-of-origin dependent fashion. This allele-specific expression is dependent on differential DNA methylation which is established in the parental germlines in a sex-specific manner. The DNA methylation imprint is accomp...

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Detalles Bibliográficos
Autores principales: Voon, Hsiao P. J., Gibbons, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819931/
https://www.ncbi.nlm.nih.gov/pubmed/26883803
http://dx.doi.org/10.1007/s00018-016-2157-6