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A phase I pharmacokinetics study comparing PF-06439535 (a potential biosimilar) with bevacizumab in healthy male volunteers

PURPOSE: This study compared the pharmacokinetics of PF-06439535, a potential bevacizumab biosimilar, to bevacizumab sourced from the European Union (bevacizumab-EU) and USA (bevacizumab-US), and of bevacizumab-EU to bevacizumab-US. METHODS: In this double-blind study, 102 healthy males, aged 21–55 ...

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Detalles Bibliográficos
Autores principales:	Knight, Beverly, Rassam, Danielle, Liao, Shanmei, Ewesuedo, Reginald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819942/ https://www.ncbi.nlm.nih.gov/pubmed/26984210 http://dx.doi.org/10.1007/s00280-016-3001-2

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