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One Loop to Rule Them All: The Ping-Pong Cycle and piRNA-Guided Silencing
The PIWI-interacting RNA (piRNA) pathway is a conserved defense mechanism that protects the genetic information of animal germ cells from the deleterious effects of molecular parasites, such as transposons. Discovered nearly a decade ago, this small RNA silencing system comprises PIWI-clade Argonaut...
Autores principales: | Czech, Benjamin, Hannon, Gregory J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Trends Journals
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819955/ https://www.ncbi.nlm.nih.gov/pubmed/26810602 http://dx.doi.org/10.1016/j.tibs.2015.12.008 |
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