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The Chemical Biology of Human Metallo-β-Lactamase Fold Proteins

The αββα metallo β-lactamase (MBL) fold (MBLf) was first observed in bacterial enzymes that catalyze the hydrolysis of almost all β-lactam antibiotics, but is now known to be widely distributed. The MBL core protein fold is present in human enzymes with diverse biological roles, including cell detox...

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Detalles Bibliográficos
Autores principales:	Pettinati, Ilaria, Brem, Jürgen, Lee, Sook Y., McHugh, Peter J., Schofield, Christopher J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Trends Journals 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819959/ https://www.ncbi.nlm.nih.gov/pubmed/26805042 http://dx.doi.org/10.1016/j.tibs.2015.12.007

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