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Virulent Mycobacterium bovis Beijing Strain Activates the NLRP7 Inflammasome in THP-1 Macrophages

Mycobacterium bovis is the causative agent of tuberculosis in a wide range of mammals, including humans. Macrophages are the first line of host defense. They secrete proinflammatory cytokines, such as interleukin-1 beta (IL-1β), in response to mycobacterial infection, but the underlying mechanisms b...

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Detalles Bibliográficos
Autores principales:	Zhou, Yang, Shah, Syed Zahid Ali, Yang, Lifeng, Zhang, Zhongqiu, Zhou, Xiangmei, Zhao, Deming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820140/ https://www.ncbi.nlm.nih.gov/pubmed/27043315 http://dx.doi.org/10.1371/journal.pone.0152853

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