Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia

Here, we report a female patient developing neuroleptic malignant syndrome following the use of a combination of clozapine and haloperidol. Subsequently, the patient presented withdrawal effects after an abrupt discontinuation of clozapine. Psychiatrists not aware of possible clozapine-withdrawal ef...

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Autores principales: Cheng, Minfeng, Gu, Huaying, Zheng, Liangrong, Wang, Houliang, Zhong, Zhiyong, Wen, Shenglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820214/
https://www.ncbi.nlm.nih.gov/pubmed/27099499
http://dx.doi.org/10.2147/NDT.S103687
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author Cheng, Minfeng
Gu, Huaying
Zheng, Liangrong
Wang, Houliang
Zhong, Zhiyong
Wen, Shenglin
author_facet Cheng, Minfeng
Gu, Huaying
Zheng, Liangrong
Wang, Houliang
Zhong, Zhiyong
Wen, Shenglin
author_sort Cheng, Minfeng
collection PubMed
description Here, we report a female patient developing neuroleptic malignant syndrome following the use of a combination of clozapine and haloperidol. Subsequently, the patient presented withdrawal effects after an abrupt discontinuation of clozapine. Psychiatrists not aware of possible clozapine-withdrawal effects may misdiagnose as a part of the primary mental illness or as the initial symptoms worsening, if unrecognized.
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spelling pubmed-48202142016-04-20 Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia Cheng, Minfeng Gu, Huaying Zheng, Liangrong Wang, Houliang Zhong, Zhiyong Wen, Shenglin Neuropsychiatr Dis Treat Case Report Here, we report a female patient developing neuroleptic malignant syndrome following the use of a combination of clozapine and haloperidol. Subsequently, the patient presented withdrawal effects after an abrupt discontinuation of clozapine. Psychiatrists not aware of possible clozapine-withdrawal effects may misdiagnose as a part of the primary mental illness or as the initial symptoms worsening, if unrecognized. Dove Medical Press 2016-03-29 /pmc/articles/PMC4820214/ /pubmed/27099499 http://dx.doi.org/10.2147/NDT.S103687 Text en © 2016 Cheng et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Case Report
Cheng, Minfeng
Gu, Huaying
Zheng, Liangrong
Wang, Houliang
Zhong, Zhiyong
Wen, Shenglin
Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia
title Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia
title_full Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia
title_fullStr Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia
title_full_unstemmed Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia
title_short Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia
title_sort neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820214/
https://www.ncbi.nlm.nih.gov/pubmed/27099499
http://dx.doi.org/10.2147/NDT.S103687
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