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Cellular Growth Arrest and Persistence from Enzyme Saturation

Metabolic efficiency depends on the balance between supply and demand of metabolites, which is sensitive to environmental and physiological fluctuations, or noise, causing shortages or surpluses in the metabolic pipeline. How cells can reliably optimize biomass production in the presence of metaboli...

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Detalles Bibliográficos
Autores principales: Ray, J. Christian J., Wickersheim, Michelle L., Jalihal, Ameya P., Adeshina, Yusuf O., Cooper, Tim F., Balázsi, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820279/
https://www.ncbi.nlm.nih.gov/pubmed/27010473
http://dx.doi.org/10.1371/journal.pcbi.1004825